Our fip dosage calculator is specifically designed to determine the appropriate concentration of active ingredients in medications for cats.
| Type of Pet | Type of FIP | Dosage (mg/kg) | Weight (kg) | Total Dose (mg) | Total Dose (mL) |
|---|---|---|---|---|---|
| Cat | Wet FIP | 6 | 2 | 12 | 0.8 |
| Dog | Dry FIP | 6 | 2 | 12 | 0.8 |
| Cat | Ocular FIP | 10 | 2 | 20 | 1.3 |
| Dog | Neurological FIP | 10 | 2 | 20 | 1.3 |
FIP Dosage Calculator
| Active Ingredient | Weight (g) | Final Volume (mL) | Calculated FIP (%) |
|---|---|---|---|
| Epinephrine | 0.1 | 10 | 1% |
| Morphine Sulfate | 0.5 | 50 | 1% |
| Gentamicin | 0.8 | 20 | 4% |
| Ketamine | 5.0 | 50 | 10% |
| Propofol | 2.0 | 100 | 2% |
| Atropine Sulfate | 0.02 | 1 | 2% |
| Aspirin | 0.5 | 25 | 2% |
| Dexamethasone | 0.5 | 10 | 5% |
| Furosemide | 0.4 | 20 | 2% |
| Amiodarone | 1.5 | 30 | 5% |
| Vancomycin | 1.0 | 50 | 2% |
| Lidocaine HCl | 2.0 | 100 | 2% |
| Bupivacaine | 0.75 | 25 | 3% |
| Ciprofloxacin | 0.3 | 10 | 3% |
| Rocuronium Bromide | 0.6 | 30 | 2% |
| Magnesium Sulfate | 1.0 | 100 | 1% |
FIP Dosage Formula
The FIP Dosage Formula is the cornerstone of accurate medication preparation.
FIP = (W/V) × 100Where:
- FIP stands for Final Injectable Product
- W represents the weight of the active ingredient
- V denotes the final volume of the solution
Suppose you’re preparing an injectable solution of lidocaine. You need to dissolve 2 grams of lidocaine hydrochloride in enough water to make a final volume of 100 mL.
Using the FIP formula:
FIP = (2 g / 100 mL) × 100 = 2%This means the final injectable product has a 2% concentration of lidocaine.
How to Calculate FIP Dosage?
Here’s a detailed explanation:
- Cat’s weight: 4 kg (8.8 lbs)
- Medication: GS-441524
- Standard dosage: 4 mg/kg/day for mild to moderate cases
- Treatment duration: 84 days (12 weeks)
Calculation Steps:
- Determine daily dosage:
- Formula: Cat’s weight (kg) × Dosage (mg/kg)
- Calculation: 4 kg × 4 mg/kg = 16 mg per day
- Calculate total dosage for treatment period:
- Formula: Daily dosage × Number of days
- Calculation: 16 mg × 84 days = 1,344 mg total
- Adjust for severity if necessary:
- For severe cases, dosage might increase to 5-6 mg/kg/day
- Example: 4 kg × 6 mg/kg = 24 mg per day
- Consider administration frequency:
- Typically, the daily dose is divided into two administrations
- For our example: 16 mg ÷ 2 = 8 mg twice daily
You need to prepare a 5% dexamethasone injection. The desired final volume is 10 mL.
- Desired concentration: 5%
- Calculate required weight of dexamethasone: (5/100) × 10 mL = 0.5 g
- Measure 0.5 g of dexamethasone
- Add suitable solvent to make up 10 mL
- Verify using FIP formula: FIP = (0.5 g / 10 mL) × 100 = 5%
The calculation confirms that you’ve achieved the desired 5% concentration.
What is FIP Dosage?
FIP dosage refers to the concentration of an active ingredient in a final injectable product, expressed as a percentage. It’s a critical concept in pharmaceutical compounding that ensures medications are prepared with the correct strength for safe and effective administration.
References
- American Society of Health-System Pharmacists. (2022). “ASHP Guidelines on Compounding Sterile Preparations.” https://www.ashp.org/pharmacy-practice/policy-positions-and-guidelines/browse-by-document-type/guidelines
- U.S. Pharmacopeia. (2023). “USP <797> Pharmaceutical Compounding – Sterile Preparations.” https://www.usp.org/compounding/general-chapter-797
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